Multidirectional wall shear stress promotes advanced coronary plaque development: comparing five shear stress metrics
نویسندگان
چکیده
منابع مشابه
Analysis of the Interdependencies Among Plaque Development, Vessel Curvature, and Wall Shear Stress in Coronary Arteries
The relationships among vascular geometry, hemodynamics, and plaque development in coronary arteries are not yet well understood. This in-vivo study was based on the observation that plaque frequently develops at the inner curvature of a vessel, presumably due to a relatively lower wall shear stress. We have shown that circumferential plaque distribution depends on the vessel curvature in the m...
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tenosis (1). The Hypertension Genetic Epidemiology Network HyperGEN) Study Group conducted a genome-wide linkage can on aortic valve sclerosis (2) that deserves to be discussed. This yperGEN cohort was a substudy of a larger National Heart, ung, and Blood Institute program, the Family Blood Pressure rogram, designed to search for hypertension/blood pressure enes. The authors reported familial a...
متن کاملWall shear stress in normal left coronary artery tree.
Despite the fact that the role of wall shear stress (WSS) as a local mechanical factor in atherogenesis is well established, its distribution over the entire normal human left coronary artery (LCA) tree has not yet been studied. A three-dimensional computer generated model of the epicardial LCA tree, based on averaged human data set extracted from angiographies, was adopted for finite-element a...
متن کاملWall Shear Stress Distribution in Patient Specific Coronary Artery Bifurcation
Problem statement: Atherogenesis is affected by hemodynamic parameters, such as wall shear stress and wall shear stress spatial gradient. These parameters are largely dependent on the geometry of arterial tree. Arterial bifurcations contain significant flow disturbances. Approach: The effects of branch angle and vessel diameter ratio at the bifurcations on the wall shear stress distribution in ...
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BACKGROUND Wall shear stress is thought to play a critical role in the local development of atherosclerotic plaque and to affect plaque vulnerability. However, current models and hypotheses do not fully explain the link between wall shear stress and local plaque development. We aimed to investigate the relation between wall shear stress and local plaque development in surgically induced common ...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2019
ISSN: 0008-6363,1755-3245
DOI: 10.1093/cvr/cvz212